Sentence examples for mutants with significant from inspiring English sources

However, it should also be noted that the use of existing clock mutants with significant growth and developmental phenotypes and different genetic backgrounds also complicates the assessment of freezing tolerance and comparison between different mutants.

In support of this model, 6 LevT-LS mutants with significant C-terminal truncations, but intact N-terminal transmembrane domains, produced lower PlevD-cat expression than those seen with the empty vector control (Figure 5).

Consistent with this model we have found that deletion of specific AP2 factors is either not tolerated or in some cases leads to mutants with significant cell cycle defects (Radke, Lucas, and White, unpublished).

Using this second approach, they identified a number of mutants with significant thermal avoidance phenotypes when tested at small ΔT.

The relationships between the 45 mutants with significant gene expression changes were investigated by hierarchical clustering of the gene expression profiles.

To identify the deletion mutants with significant morphological changes beyond those of the natural strains, we performed a one-sample test with a normal distribution based on the PC scores in PC1 − PC4.

Selection of mutants with a significant D-xylose anaerobic fermentation rate is a challenging task, because likely multiple mutations are required [ 10].

However, the identification of mutants with no significant variations in the amount of chitin indicates that CWI pathway activation could be due to alternative stimuli or internal inputs on this signaling route.

We report that fixation of less costly kanamycin-resistant mutants occurred earlier in populations growing at lower sublethal concentration of the antibiotic, compared with those growing at higher sublethal concentrations; in the latter, resistant mutants with a significant growth defect persisted longer.

Analyses of these data reveal that there were very similar trends between the wild-type enzyme and each of the 4 mutants, with a significant reduction in the bypass efficiencies of TLS for all mutants tested when replicating DNAs containing adducts in either the major or the minor groove.

Anatomical features reveal secondary xylem activity in "thick stem" mutant along with significant enhancement in fibre zone, number of fibre pyramids and fibre bundles per pyramid, and diameter of fibre cell in relation to control.