Sentence examples for mediate cell motility from inspiring English sources

PI3K can mediate cell motility through the activation of small GTPases.

In single cells, syndecan-1 activates formation of filopodia and lamellipodia that mediate cell motility [ 12, 13].

Hepatocyte growth factor (HGF) and its receptor tyrosine kinase c-Met mediate cell motility, migration, increased tumor local invasion, and metastasis (Knudsen & Edlund 2004).

The same group also determined a role for XIAP RhoGDI interaction via RING domain of XIAP to mediate cell motility by regulating actin cytoskeleton.

In this study, we revealed that activation of HSP27 and p38, which mediate cell motility and migration, was downregulated by inhibition of T βR-I fucosylation induced by siFUT3 and siFUT6, resulting in the suppression of EMT.

S1Pext mediates cell motility through activation of Rac1 and IQGAP1 signal transduction in HPAECs.

Nexilin is a F-actin binding protein and mediates cell motility, over-expression of which promoted cell migration and adhesion[46].

TNC has been also implicated in mediating cell motility and invasion in a variety of epithelial cancers.

In contrast, IGF-I did not stimulate cell motility in T47D-YA/IRS-1 cells, suggesting a functional specificity of IRS-2 in IGF-IR-mediated cell motility.

Previous work in our lab suggests a role for IRS-2 in mediating cell motility in highly metastatic breast cancer cell lines (Jackson et al, 2001).

HMMR is a multicompartmentalized receptor for the extracellular matrix carbohydrate HA with potentially oncogenic functions such as mediating cell motility and affecting mitotic spindle integrity [ 35].