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ILK is an intracellular serine/threonine protein kinase that is a constituent of integrin-mediated cell-matrix focal adhesions, structures that mediate cell adhesion and signal transduction between the extracellular matrix and the intracellular compartment [ 6].
Early on, it was recognised that OPN had adhesive activity, confirmed by the observation that its receptors all mediate cell adhesion.
Integrin receptors mediate cell adhesion to extracellular matrices and trigger signals that direct cell function.
Transmembrane adhesion receptors, such as integrins, mediate cell adhesion by interacting with intracellular proteins that connect to the cytoskeleton.
Cell adhesion on the surface of such implants is necessary for better integration with the neighbouring tissue; however, hydrophobin surfaces do not mediate cell adhesion.
Because heparan sulfate proteoglycans mediate cell adhesion and control the activities of numerous growth and motility factors, they play a critical role in regulating the metastatic behavior of tumor cells.
Here, we propose that the plant lectin WGA (wheat germ agglutinin), covalently bound to SF, will mediate cell adhesion in a time frame acceptable to be part of a one-step surgical intervention.
Similar(4)
Bisecting glycans were shown to increase E-cadherin-mediated cell adhesion and reduce integrin-mediated cell spreading and migration [13].
By the upregulation of EpCAM, E-cadherin-mediated cell adhesion diminishes and the EpCAM-mediated adhesion may predominate (Went et al, 2006).
Integrin mediated adhesion was examined using the α/β Integrin-mediated cell adhesion array combo kits (Chemicon, UK).
By upregulation of Ep-CAM, E-cadherin-mediated cell adhesion diminishes and the Ep-CAM mediated adhesion becomes predominant.
More suggestions(15)
mediate cell death
mediate cell growth
mediate cell motility
mediate cell internalization
mediate intermembrane adhesion
mediate cell sorting
mediate cell cycle
mediate cell invasion
mediate platelet adhesion
mediate cell hyperproliferation
mediate cell differentiation
mediate leukocyte adhesion
mediate cell fate
mediate cell contraction
mediate cell migration
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