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Next, we wondered whether the RA-mediated TrkB up-regulation and activation mediate cell differentiation.
Paracrine transfer of chemical factors between two interacting cells is a fundamental biological signaling process that can mediate cell differentiation, proliferation or even cell death.
Ret stimulation in turn is crucial to mediate cell differentiation [18].
To further investigate whether STIM1 and Orai1 mediate cell differentiation, A2B5+ NPCs were individually transfected with siRNA of STIM1, Orai1, or both of them, and then cultured in differentiation conditions.
Surprisingly, mTOR bearing an additional mutation that abolishes its kinase activity could also mediate cell differentiation.
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Tissue engineering is replete with methods for inducing and mediating cell differentiation, which are crucial for ensuring proper regrowth of desired tissues.
Dear Editor, Heat shock factors (HSFs) constitute a transcription factor family playing regulatory roles in maintaining cellular protein homeostasis or mediating cell differentiation and development (Akerfelt et al., 2010, Bjork and Sistonen 2010, Westerheide et al., 2012).
This is in agreement with a previous report that CD44 mediates cell differentiation [58].
The FRUITFULL (FUL) gene mediates cell differentiation during A. thaliana fruit development [ 31].
It is in the central of a molecular metabolic network that mediates cell differentiation and proliferation.
In response to physiological clues, bidirectional integrin signaling mediates cell differentiation, proliferation, homing, migration and survival[ 5, 6].
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mediate cell division
mediating cell differentiation
mediate cell lysis
mediate cell morphology
mediate terminal differentiation
mediate cell death
mediate epicardium differentiation
mediate cell growth
mediate osteoblast differentiation
mediate cell motility
mediate cell adhesion
mediate cell entry
mediate cell internalization
mediate cell hyperproliferation
mediate cell fate
mediate cell contraction
mediate prostate differentiation
mediate cell attachment
mediate monocyte differentiation
mediate cell migration
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