Sentence examples for mediate cell movement from inspiring English sources
Integrins are cell surface receptors involved in adhering cells to the ECM and mediate cell movement [ 26].
This is related to the differential ability of the progestins to activate the actin-binding protein moesin, leading to distinct effects on actin cytoskeleton remodeling and on the formation of cell membrane structures that mediate cell movement.
The small Ras-like GTPase rap-1 has been shown to act in concert with the RAL-1/exocyst pathway in mediating hypodermal cell movement and elongation during embryonic development in C. elegans (Frische et al. 2007).
In their study, C4 localized at the cell periphery and had a limited capacity to mediate cell-to-cell movement of viral DNA [29].
We have previously demonstrated that Rho mediates gastrulation cell movements in zebrafish via Rho-associated kinase [29] and Diaphanous [28], by regulating the contractile activity of actin filaments.
These results showed that zDia2 and zPfnI synergistically mediates the gastrulation cell movement in zebrafish.
The results of figure 1 imply that the direction of cell movement is mediated by pseudopodia that are extended at the side of the cell closest to the gradient.
The physical force required for this collective cell movement is mediated at least in part by the supercellular F-actin myosin cable or 'purse string' (visualized by phalloidin staining; see below) drawing the surrounding cells inward towards the site of the damage (Slattum et al., 2009).
FAK activation was shown to mediate Akt phosphorylation which resulted in cell movement.
Our findings suggest that Dictyostelium cells spontaneously create the ordered patterns of cell shape mediated by PI3K/PTEN/F-actin and control the direction of cell movement by coordination with these patterns even in the absence of external stimuli.
In conclusion, our findings manifest that progesterone and MPA promote breast cancer cell movement via rapid actin cytoskeleton remodeling, which are mediated by moesin activation.
