Sentence examples for modulate disease progression from inspiring English sources

LncRNAs regulate gene expression, thus having the possibility to modulate disease progression.

Targeted therapies are used to modulate disease progression by inhibiting a specific protein within a dysregulated signaling pathway [ 2].

From these results, we hypothesized that a key molecule involved in AD pathogenesis is modified with this sugar chain to modulate disease progression.

In order to determine the possible clinical relevance of such LF-treated DC for inducing antigen-specific tolerance or hyporesponsiveness, we assessed their ability to modulate disease progression in the murine CIA, as an experimental model of RA.

Besides differences in size, post-translational modifications of Aβ – including oxidation, phosphorylation, nitration, racemization, isomerization, pyroglutamylation, and glycosylation – generate a plethora of peptides with different physiological and pathological properties that may modulate disease progression.

For example, human bone marrow-derived MSCs (hBM-MSCs) improved functional recovery in both chronic and relapsing-remitting models of mouse EAE, traced their migration into the injured CNS, and assayed their ability to modulate disease progression and the host immune response [ 9].

This correlation is not absolute, suggesting the existence of yet unknown factors modulating disease progression.

It is now widely recognised that neuroinflammation is a prominent feature of AD brain, with inflammatory responses playing a significant role in modulating disease progression.

Rarely, patients with two SMN2 copies show mild phenotypes (9), suggesting the influence of yet unidentified modifying factors modulating disease progression.

Treatment of TNF-driven Tg197 transgenic mice with PIP-18 significantly modulates disease progression by suppressing arthritis indicators (synovitis, cartilage and bone erosion) as well as circulatory levels of murine sPLA2, IL-6, and human TNF-α.

From a distance, the interaction between disease and depressive disorders confers no pattern of protection or susceptibility in terms of sex steroids; rather, the unique properties of the disease states in conjunction with sex steroids interact to modulate disease symptomology, progression, and mortality.