Sentence examples for modulate disease development from inspiring English sources

TLR3 in mLN and TLR7 in spleen both systemically modulate disease development in AIPI rats via altering serum IgE concentration relevant to Th2 responses.

TNF antagonists modulate disease development mainly by their anti-inflammatory properties.

However, studies determining the effects of antibiotics in modulating disease development have not assessed whether reduction of what could be considered "pro-diabetogenic" flora, or alternatively, an overgrowth of protective flora occurs.

In addition, identification of the important pathways in human pathogenesis in relation to these exposures may yield evidence-based opportunities to modulate the course of disease development.

Examinations of genetic polymorphisms in the VDR as a factor in modulating PD risk or disease development have produced variable results [ 38].

Although the beneficial effects of probiotics on wide variety of atopic diseases have been suggested, little is known about how probiotics modulate the immune system, atopic disease development, and skin allergy reactions.

This would suggest that modulation of Treg-cell numbers by B/cWKO Breg cells is specific to disease development, but may not be sufficient to modulate Treg-cell function.

The regulatory network analysis revealed that several host cellular factors, implicated in HIV-1 disease progression, might be modulated through miRNA regulation of gene expression during disease development.

The development of new therapeutic tools directed to modulate disease effector molecules is therefore required.

The weak associations identified for a number of hypothesised risk factors imply that multiple pathways may be involved in disease development, and as with other multifactorial diseases, gene interactions with environmental factors may also modulate disease risk [ 48- 56].

Changes in SLRP levels could also significantly modulate the action of potential anabolic factors such as TGF-β and its downstream effector CTGF, possibly adding to disease development.