Sentence examples for modulate disease pathogenesis from inspiring English sources

The Notch ligand DLL4, a key molecule in Th-cell differentiation was reported to modulate disease pathogenesis during allergen-dependent inflammation and respiratory viral infection.

The binding of C5aR to the ligand can modulate disease pathogenesis by regulating the balance of activating and inhibitory FcγR receptors [ 41, 42].

Studies by the same group previously showed that NLK could modulate SCA1 disease pathogenesis, SCA1 being another polyglutamine disorder.

These observations collectively implicate that autophagy is an important modulator of disease pathogenesis.

Anandamide and 2-AG act mainly on CB1 and CB2 receptors to modulate both normal physiology and disease pathogenesis in a host of biological systems, including nociceptive processing (reviewed in [15]).

Infectious diseases modulate apoptosis and this contributes to disease pathogenesis.

For example, binding of the ligands could trigger the conformational changes in some of the Trypanosomal enzymes to modulate their activity leading to the disease pathogenesis [48], [49].

Several new strategies are being explored as therapeutic modalities to modulate the crucial contribution of monocytes/macrophages to fibrotic disease pathogenesis.

This study underlines the role of sCTLA-4 in modulating the immune response and its relevance in autoimmune disease pathogenesis.

From these results, we hypothesized that a key molecule involved in AD pathogenesis is modified with this sugar chain to modulate disease progression.

These findings imply that HIF-1α is involved in the pathogenesis of renal injury, as activation of HIF responses could modulate disease activity at an early stage, when tissue oxygenation is not yet impaired.