Sentence examples for modulate disease phenotype from inspiring English sources

Newly acquired genomic tools now allow the identification of genetic and epigenetic factors that can either increase ALS risk or modulate disease phenotype.

These lesions also showed mosaic expression of SNF5 by immunohistochemistry. Therefore, our studies implicate that modest changes in angiogenic regulation interact with perturbations of SWI/SNF complex activity to modulate disease phenotypes.

In this regard, genes capable of modulating disease phenotype only in a specific ND give us hints to understand the difference in disease progression.

Sex chromosome-dependent gene expression variation in immune response genes might be one pathway for modulating disease phenotypes.

Modifiers are genes that are capable of modulating disease phenotypes; in this case the neuronal cell death caused by protein aggregation.

Therefore, the degree of reduction of C9orf72 may well modulate the disease phenotype.

The efficiency of activating latent transforming growth factor (TGF -β1 in sysTGF -β1upus erythematosus (SLE) may control the balance between inflammation and fibrosystemiculupusg therythematosusnotype.

NMD has been shown to modulate human disease phenotypes.

DOI: http://dx.doi.org/10.7554/eLife.08493.007 We next wondered whether NLK could modulate SBMA disease phenotypes.

This study identified specific and prioritized sets of key nodes in hepatic molecular networks underlying T2DM, uncovering pathways that are to be modulated by targeted T2DM drug interventions in order to modulate the complex disease phenotype.

IP-10 is also regulated by other cytokines including IFN-α, IL-1β and IL-12 [17], [18], [18], disease phenotype can modulate cytokine half-life [19], and there may be differential cellular uptake and cellular regulation of IP-10 [17].