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The development of new therapeutic tools directed to modulate disease effector molecules is therefore required.
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However, whether TGA family proteins in lily modulate disease resistance through ROS accumulation is unknown.
Later on in childhood, P. aeruginosa predominates and modulates disease outcome substantially [3].
Satellites are capable of modulating disease expression, however (19).
Table 1 Examples of modifications to modulate antibody effector function.
The balance between TNF-α and IL-10 could modulate the effector function of macrophages and cellular apoptosis.
The polymorphism of amyloid forms and their distribution are both effectors that potentially modulate the disease, thus it is important to understand the molecular basis of protein amyloid disorders through the interaction of the different amyloid forms with neural cells and tissues.
The wealth of information generated about antibodies has afforded investigators the ability to molecularly engineer antibodies to modulate effector functions.
There are several ways in which investigators have mutated the amino acid sequence of the IgG Fc region to modulate FcγR-based effector function.
In the immune system, miRNAs act at checkpoints during hematopoietic development and cell subset differentiation, they modulate effector cell function, and are implicated in the maintenance of homeostasis.
However, the mechanisms by which changes in cellular tension modulate effector activity remain unclear.
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