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While this evidence would support the direct pathogenicity of ANCA, the observation that patients with high-titer ANCA can lack glomerulonephritis and may remain in remission suggests that additional factors modulate disease occurrence in humans.
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Given the wide range of HIF-regulated biological functions, normoxic stabilization of HIF-1α is likely to modulate disease activity at an early stage before the occurrence of significant hypoxia.
He described his larger interest as an "instinctive search for patterns in designs, disease occurrence or clustering of any sort".
However, their effect on bacterial colonization and peri-implant disease occurrence has been poorly investigated.
However, whether TGA family proteins in lily modulate disease resistance through ROS accumulation is unknown.
Thus, there is compelling evidence suggesting that the Notch pathway is activated in RA and may modulate disease activities.
To date, more than 100 variants that modulate disease susceptibility have been identified.
The study involved factors such as population density and elevation difference in conjunction with the types of transport networks to predict the disease occurrence in space.
In analysis of disease occurrence, in vitro systems which use cell culture dishes are often used.
The variation in disease occurrence was largely dependent on cow-level factors.
We therefore studied double mutant female mice and hypothesized that short telomeres would modulate disease severity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com