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We therefore studied double mutant female mice and hypothesized that short telomeres would modulate disease severity.
Treatment with a COX-1 inhibitor during influenza A viral infection is detrimental to the host whereas inhibition of COX-2 does not significantly modulate disease severity.
In summary, we have shown that treatment with a COX-1 inhibitor during influenza A viral infection is detrimental to the host, whereas treatment with a COX-2 selective inhibitor does not significantly modulate disease severity.
A range of protective immunological responses are involved that modulate disease severity and survival.
We aimed to derive correlations between the gene expression changes in PKD and a set of pathways that modulate disease severity in our mouse model and human ADPKD.
Wiese et al. studied the ability of supplementing two 8-ounce cans of an ONS containing fish oil, antioxidants, and prebiotics in CD patients to modulate disease severity [ 38].
Similar(52)
However, its role in predisposing to, or modulating disease severity in, Clostridium difficile infection (CDI) has not been investigated.
These findings suggest a prominent role for IL-10-producing Breg cells in modulating disease severity and for control of autoimmune of autoinflammatory processes.
C4bp, and thus negative regulation of the classical pathway of complement activation, therefore appears to play a minimal role in modulating disease severity in the MRL mouse.
There is potential that these genetic susceptibility factors could also modulate MS disease severity, as demonstrated previously for the MS risk allele HLA-DR15.
As shown in our study, there could be considerable role of pre-existing T cellular immunity in modulating the disease severity of pandemic strains even in the absence of pre-existing neutralizing antibodies.
Related(18)
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