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TPX2 has been discovered over 17 years ago for its unique property to mediate cell division.
Tubulins are a family of eukaryotic structural genes that form microtubules, fundamental components of the cytoskeleton that mediate cell division, shape, motility, and intracellular trafficking.
We examined the association of inherited variation in genes from pathways that mediate cell division with percent mammographic density (PMD) adjusted for age, body mass index (BMI) and postmenopausal hormones, in two studies of healthy postmenopausal women.
We show that the predicted HLH-25 transcriptional network, based on gene expression microarray, includes the Pten ortholog DAF-18 and other genes that mediate cell division, embryonic development, and larval development.
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FGFR2 is a receptor tyrosine kinase mediating cell division, growth and differentiation signaling.
It is possible that a LexA target interacts with FtsZ in C. crescentus, to mediate the cell division arrest observed upon starvation [10].
The function of Fat and Dachsous in controlling PCP is conserved in mammals [ 30], suggesting that dach should have mammalian orthologs to mediate polarized cell division.
A gene involved in reproductive organogenesis encoding the WD40 domain protein SLOW WALKER1 (Swhich whish is known to mediate mitotic cell division during female gametogenesis [ 37] was also directly connected to this central AT5G19300 node.
ZipA is a membrane anchored protein in Escherichia coli that interacts with FtsZ, a homolog of eukaryotic tubulins, forming a septal ring structure that mediates bacterial cell division.
Polarized distribution of Dachs in the cell then mediates oriented cell division in Drosophila [ 13].
SulA, one of several key factors induced by the SOS response to DNA damage, has been shown to mediate inhibition of cell division in E. coli26,27.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com