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Obviously the evolved purpose of BAH-1 is not to mediate adherence of a deleterious microbial product.
Their primary, though not exclusive, biological role is to mediate adherence of fungal cells, possibly with different members of the family being differentially involved in the adherence to different host cells and tissues [75].
ICAM-1 is a member of the immunoglobulin-like supergene family of adhesion molecules known to mediate adherence of polymorphonuclear neutrophils (PMNs) to endothelial cells [ 18].
The presence of EAEC virulence factors, such as aggregative adherence fimbria AAFI and aggR, can mediate adherence of E. coli to bladder epithelial cells, but the virulence factors do not impart uropathogenic properties to all EAEC isolates (10 ).
In capsulate bacteria, pilus interactions dominate, yet, in the presence of certain pilus structures with lowered adhesion capacity, Opa proteins also mediate adherence of capsulate meningococci to the meningioma cells [ 141].
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Our data show an unexpected role of the meningococcal PilC2 variant in efficiently mediating adherence of Nme to ME180 cells, a role thought to be restricted to PilC1.
Previous studies had shown that OmpP should be regarded as a potentially suitable subunit vaccine component, for it can not only serve as a highly conserved adhesin mediating adherence of B.p or B.parapertussis (B.pp) to human bronchial epithelial cells in vitro but also induce long-term high titers of bactericidal antibodies in immunized mice [38], [39].
PRN is a 69-kDa outer membrane protein that mediates adherence of the bacterium to host cell walls.
The interaction between leukocyte-function-associated antigen (LFA -1 and ICAM-1 mediates adherence of LFA -1ytes to endotheliandcells, facilitating migration of inflamediatescells to infladherences [ 40].
Mutations in the LAMP2 gene have been identified in patients with hypertrophic cardiomyopathy[ 29], and the gene product mediates adherence of PBMCs to the vascular endothelium[ 13].
Evidence was provided that the HMW subunit functions as an adhesin which mediates adherence of C. difficile to host cells (Calabi et al., 2002).
Related(20)
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