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These specialized immune proteins mediate recognition of diverse pathogen-derived effector proteins and initiate potent defense responses.
As mentioned above, many DNA sensors have been defined to mediate recognition of exogenous DNAs.
All 17 BORIS isoproteins contain a ZF DNA binding domain that can mediate recognition of specific DNA targets.
Indeed, both ESPs and MUPs have been hypothesized to mediate recognition of individual characteristics including gender [68], rather than recognition of subspecies.
In the future, the identification of novel surface receptors that associate with NbSERK3A and/or NbSERK3B should lead to the identification of new receptors that mediate recognition of oomycete PAMPs, such as INF1.
Indeed, a training study of novel objects and their functions [22] indicates that the left lateral (pMTG, SMG/IPL) and left ventral (medial FG) areas mediate recognition of trained artificial objects and their functions.
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Wang, X. et al. Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor.
Toll-like receptor 9 (TLR9) is a pattern recognition receptor that mediates recognition of Mtb and modulates Mtb-specific T-cell responses.
The DC-SIGN-mediated recognition of Leishmania amastigotes does not induce DC maturation, and the DC-SIGN ligand/s on Leishmania parasites is/are still unknown.
TLR2 mediates recognition of live SE and clearance of SE bacteremia in vivo.
It will be interesting to determine if any of these mediates recognition of M. luteus and in vivo host defense.
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