Sentence examples for mutations that disturb from inspiring English sources

In agreement with a previous screen for mutations that disturb glycogen metabolism [32], deletion of YIL057C leads to an enhanced glycogen accumulation in growing cells, while deletion of YER067W shows no phenotype in this situation.

Gene regulation is thought to be in a well-balanced state, and any mutations that disturb the balance are deleterious.

This view is not acceptable because we know that any hybrid sterility genes are mere consequence of mutations that disturb the gene interaction systems in interspecific hybrids.

Badcock and Crespi have advanced the bold hypothesis that most cases are caused by mutations that disturb developmental pathways modulated by imprinted genes.

Mutations that disturb alternative splicing regulation lead to an increase in the 4R form over 3R, and (along with missense mutations in exon 10) are associated with a tauopathy composed of four-repeat tau.

A mutated variant of the immunodominant C-terminal domain of the group 1 grass pollen allergen Phl p 1 was recently established through an approach that used a set of human monoclonal IgE as a guide to identify mutations that disturbed IgE-allergen interactions.

Furthermore, a FOXP3 mutation that disturbs dimerisation results in immunodysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.

Inside stems, a mutation that disturbs the correct base pairing is likely to reduce molecular fitness.

The change of carbon source seemed to affect mainly the energy metabolism of the cells, whereas a mutation that disturbs the carbon repression mechanism seemed to have a significant impact on the amino acid metabolism.

Gene mutations and other factors that disturb the normal maturation pattern of chondrocytes generally result in chondrodysplasias and other forms of dwarfism and skeletal deformities [ 4].

Neurodevelopmental disorders that disturb speech and language are highly heritable.