Sentence examples for mutations that improve from inspiring English sources

Moreover, if the structure of the metabolic and regulatory networks and their component genes yielded relatively few genetic pathways with which to improve growth on glucose, it is unlikely that the multi-step mutational pathway to Cit+ that first required mutations that improve acetate utilization would ever have been realized.

Directed evolution identified two point mutations that improve affinity to 180 pM.

Furthermore, mutations that improve the simulated integration efficiency likewise increase the experimentally observed expression levels.

Finally, mutations that improve the fit to one environment may dis-improve the fit to another: specializing may come with a cost.

In other words, do the mutations that improve performance in the tough environment come with a fitness cost in the relaxed one, and if so, how large a cost is it?

Mutations that improve the activity of the PAI-2 signal sequence and that convert the N-terminal regions of maspin and PI-10 into efficient signal sequences have been characterized.

This tradeoff could be overcome by simultaneous introduction of separate mutations that improved mating efficiency alongside those that improved discrimination.

So a lot of modern plant strains were created by applying chemicals or radiation to cause mutations that improved the crop.

Utilizing structural information, we have designed and generated a number of rational BMP-7 mutations that improved both expression levels in mammalian cells and solubility at neutral pH, while limiting the amino-terminal heterogeneity of the mature protein.

We found evidence that the clade in which Cit+ would eventually evolve had previously evolved a suite of mutations that improved the utilization of acetate.

However, there are counterexamples where improved tolerance does not lead to an increase in biofuel production, for example Atsumi et al. identified mutations that improved isobutanol-tolerance in E. coli.