Sentence examples for mutations that hinder from inspiring English sources

Intriguingly, SAP30L seemed to be bound more tightly than SAP30, suggesting that SAP30 has accumulated mutations that hinder its association with the nuclear matrix.

Such age-dependent distribution of PQSs can be explained by the action of constraints leading to fixation of quadruplexes in recent and active elements while non-active older elements accumulate mutations that hinder quadruplex formation.

This expression silencing may be attributed either to genomic (e.g. DNA deletions, somatic mutations in promoter regions that hinder TF binding, transcript-truncating alterations, etc).

Further work will address mutation co-reference resolution; In journal papers, very often the authors use pronominal or nominal mutation references that hinders the grounding of impacts.

Dr. Majzoub and his colleagues are now trying to determine whether additional mutations in the gene they discovered — ones that hinder its function but do not completely disable it — might explain why some people gain weight.

Urban elements that hinder social interactions are undesirable.

A number of barriers that hinder MNH services were discussed.

It also suggests that insulin resistance in Dahl S rats might still be mediated via defects in the insulin receptor substrates –1 and/or –2, possibly genetic mutation(s) that hinder(s) their association with downstream molecules in the insulin signaling pathway and prevent(s) glucose uptake by the cells.

The biggest thing that hinders us is fog".

"That hinders drug development".

This means that the fate of each beneficial mutation depends on many parameters: mutation rate, population size, and the distribution of fitness effects all control the availability of competing mutations that can help or hinder the spread of each new beneficial mutation (G errish and L enski 1998; W ilke 2004; D esai and F isher 2007; F ogle et al. 2008; R ouzine et al. 2008).