Sentence examples for mutations that interrupt from inspiring English sources

Second, the extent to which the effect of mutations that interrupt or overstimulate signaling pathways can be counteracted by the action of drugs must be assessed.

What are the mutations that interrupt growth inhibition by TGF-β and confer growth advantages at an early stage of tumor development?

Closer inspection revealed that these instances were generally due to a stop codon or frameshift mutation that interrupted the ORF, causing it to be annotated as two genes with identical function.

Chondrocyte hypertrophy could be delayed in mice with a PTH1R mutation that specifically interrupted the PLC/PKC pathway but did not affect cAMP/PKA activation [ 43].

Mutations that add or change function?

Somewhere among the genetic disparities must lie the mutation or, more probably, mutations that define us.

The IDH-2 mutation is just one of many enzyme mutations that are found in acute myelogenous leukemia.

Avoid asides that interrupt the flow of the text.

Evolution depends on mutations that simply don't have direction.

This finding corroborates previous suggestions that interrupted motifs reduce stutter and therefore result from mechanisms of mutation (e.g., due to slippage in replication; Richards and Sutherland, 1992, 1994; Pépin et al., 1995; Petes et al., 1997; Rossetto, 2001).

That interrupts their ability to grieve.