Sentence examples for mutations at random from inspiring English sources

Thus RDL mutagenesis is an efficient method for targeting mutations at random to a single domain of the yeast genome.

The properties of sequence variability in the sample can be modeled by throwing mutations at random onto the tree (Hudson 1990).

Mutagenesis via chemicals or transposons is used to create mutations at random sites of the genome, and it has to be followed with screenings to identify phenotypes of interests.

After the loss of teeth 100-80 mya, the four dental proteins became no longer useful; when the functional pressure relaxed on the coding genes, they started to accumulate mutations at random.

For this reason, it is likely that the CORE-GS will also improve the efficiency of the several modifications of SSG described previously: namely, replacing alleles (asSSG), inserting (iSSG) or deleting (dSSG) sequences, or introducing mutations at random within a defined region of the genome (RDL mutagenesis) [ 14, 15].

Our model performed calculation under two hypotheses, which are commonly adopted and have lead to accurate prediction in the study of HIV-1 virus [ 10]: first, nucleotide variation of these strains occurred by independent mutations at random positions in a single ancestral sequence; second, there exist a molecular clock and a constant rate of evolution.

Furthermore, in the aging, human colon somatic mtDNA mutations occur at random and are commonly nonsynonymous or frameshift mutations that are significantly more pathogenic than germline variants (Greaves et al., 2012).

Mutants identified to be hypercytotoxic in vitro were more likely to be avirulent (12 of 28 strains, 43%) as compared to transposon insertion mutations screened at random for virulence in which 4 6% of insertion mutations were avirulent [21].

Mutations arise at random, but clearly this does not mean that evolutionary change is random.

Mating is often non-random, and of course, many neutral and silent mutations occur at random.

For many such changes, Barron says, genetic mutations happening at random mimic the effects of the drug.