Sentence examples for mutations at early from inspiring English sources

A cost-effective method for screening deafness-associated mutations at early age is needed.

However, little is known regarding evolution of the HCC-related mutations at early stage of chronic infection.

In addition, PIK3CA mutation occurs early in oncogenesis and is associated with ductal hyperplasias, while TP53 mutations at early stages have not been found [ 35, 12].

As this abnormality affects the last exon, studying its role is not as straight forward as other splicing mutations at earlier exons.

Identification of clinically-actionable mutations at an early stage could lead to targeted treatment before tumor heterogeneity and multiple genomically-distinct clones that are resistant to therapy can evolve.

Remarkably, K101Q was observed along with the double mutations at the early time of antiviral therapy.

1 A subpopulation of isolated del 5q) MDS patients has TP53 mutations at the early stage of the disease, which is associated with an increased risk of leukemic evolution.

However, in several recent reports, it has been shown that the occurrence of mismatch repair (MMR) gene mutations at an early stage might be significant in tumourigenesis through KRAS mutation in MSI-H CRC.

Considering cell proliferation in embryogenesis, an pSNM with relatively higher mutant allele fraction might be more likely generated by postzygotic mutations at the early developmental stage and, therefore, be more likely shared between somatic and germ cells.

CSF samples from 23 asymptomatic and seven symptomatic LRRK2 mutation carriers at early stages (subjects with UPDRS > 20 were excluded to allow exclusive focus on early PD) were assessed.

Overall reverse mutations appeared at earlier time points than escape mutations from the wild type.