Of course, fitness advantages will also differ between mutations at different loci, even within the same cancer type.
From the result of mutational analysis (summarized in Table 2), some unique mutations at different geographical locations were found.
The difference in the pattern of non-conservative mutations at different levels of iFLC suggests that non-conservative mutations in key areas of the immunoglobulin light chain may affect the rate of amyloidogenesis of the protein.
However, the guidelines do not address whether truncating mutations at different positions along the length of the protein might differ in phenotype severity or mechanism of action, a finding that could complicate interpretation of truncation mutations for a broad range of inherited diseases.
Occurence of deletions and other mutations at different rates in different portions of the cluster results in a complex process of aflatoxin biosynthesis loss.
In this study, four combinatorial phage libraries displaying AL mutants with random mutations at different amino acid positions in the A domain were constructed.
Recent reports identified nonsense, missense, and splicing mutations at different exons of ANTXR1 responsible for GAPO syndrome in patients from different ethnic populations.
To test the interdomain communicating function of the two short parallel β-sheets, we disrupted the β-sheet formation by introducing point mutations at different positions in the four β-strands.
The mutations at different positions, even distantly separated, are mutually coupled and form an evolutionary network.
