Sentence examples for mutations at residue from inspiring English sources

In contrast, mutations at residue L35 appear to be important for obtaining good (S,S -2 variantS,S -2

We have performed site directed mutagenesis to introduce two mutations at residue Thr84, T84A and T84S, to explore the binding affinity of the substrate and the catalytic mechanism.

We further examined whether the mutations at residue 70 affect susceptibility to NRTIs in the Q151Mc background (Figure 2B and also Table S3).

Reciprocal Cys<->Ser mutations at residue 67 of the native Nv-NF-κB proteins affect DNA binding as in human NF-κB proteins, e.g., a Cys->Ser mutation increases DNA binding of the native Cys variant.

Only patients who had VF (defined as plasma HIV-1 RNA>400 copies/ml after three months on RAL and/or >50 copies/ml after six months on RAL) with selection of mutations at residue 143 were included in this study.

This, accompanied by mutations at residue 67, may affect substrate selectivity of the enzyme preventing incorporation of drug-triphopsphates.

All highly active clones encoded one or more mutations at residues 32, 176, or 234.

Thus, mutations at residues near the binding interface can also abolish the function of the binding interface.

Mutations at residues D163A and N170R, on the other hand, reduced the binding affinity of Envgp120-C3d2 for sCR2.

Single and double mutations at residues Q20 and D43 were made in a recombinant expression system that corresponded to Gox2181-D43Q and Gox2181-Q20R&D43Q, respectively.

Multi-drug resistant (MDR) 769 HIV-1 protease (resistant mutations at residues 10, 36, 46, 54, 62, 63, 71, 82, 84, 90) was selected for the present study to understand the binding to its natural substrates.