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More Ki-67 positive cells were detected in AT2-KO mouse tumor sections than in wild type mouse tumor sections.
To evaluate the killing mechanism of transfected cells treated with GCV, TUNEL assays were performed on mouse tumor sections.
To determine whether the molecular events observed in cell lines were also found in mice, we performed immunohistological staining and TUNEL assay of mouse tumor sections.
Consistently, melanoma blood vessels in DKK1 Tg mouse tumor sections stained less for beta-catenin (37 % reduction) compared with that in control mice (Fig. S1a, b).
To verify the existence of a VEGF autocrine loop in SS, mouse tumor sections were examined histologically; expression of both VEGF-A and VEGFR2 was detected in the tumor (Fig. 3c).
Mouse tumor sections used for SEM as well as AFM studies were obtained by establishing tumors in nude mice treated with either control B16F1 mouse melanoma cells or with SMAR1-P44 peptide [ 42].
Similar(52)
Decreased tumor size following metformin treatment was due to the reduced proliferation status of tumor cells as shown by Ki-67 staining on mice tumor sections.
To search for more evidence of tumor cell apoptosis and necroptosis, TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling assay) assay and ultrastructural study were also performed on mice tumor sections, respectively.
To investigate tumor vessel density in WT and EC JAM-C-KO mice, tumor sections from both strains were analyzed for VE-cadherin expression by immunofluorescent staining and confocal microscopy (Fig. 4 A C ) or were measured for the EC protein endomucin by Western blot (Fig. 4 D, E).
The representative H&E stained and IHC images of mouse lung tumor sections are shown.
An increase in the number of TUNEL-positive cells, increased Bax expression, and decreased Bcl-2 expression in nude mice brain tumor sections and brain tissue lysates confirm our in vitro results.
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mouse tissue sections
mouse tumor groups
mouse brain sections
mouse heart sections
mouse lung sections
mouse liver sections
mouse tumor specimens
mouse eye sections
mouse skin sections
mouse tumor cultures
mouse embryo sections
mouse kidney sections
mouse tumor data
mouse lens sections
mouse tumor models
mouse tumor passages
mouse cryostat sections
mouse tumor xenografts
mouse tumor cells
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