Sentence examples for mouse tumor groups from inspiring English sources

This second peak was not shared with the mouse tumor groups.

Likewise, the chromosome 13 loss, associated with RB1 loss [ 38] occurs in all human and mouse tumor groups, and all overlapping regions encompass the INTS6 gene.

Regional CNAs that occur significantly more often in the Brca1 Δ/Δ ;p53 Δ/Δ or Brca2 Δ/Δ ;p53 Δ/Δ mouse tumor groups compared with the p53 Δ/Δ control tumors are listed in Additional file 7.

Indeed, all human tumor groups showed a recurrent gain on chromosome 8q, likewise all mouse tumor groups showed a recurrent gain on its syntenic region, on chromosome 15, centering exactly on the MYC oncogene.

We determined which genes from this list map to the significantly gained or lost regions as determined by KC-SMART method or to the differentially gained or lost regions as determined by the comparative-KC-SMART method for the human and mouse tumor groups separately.

In all mouse tumor groups, the peak of this gain was located at (for Brca2 Δ/Δ ;p53 Δ/Δ and p53 Δ/Δ tumors) or near (for Brca1 Δ/Δ ;p53 Δ/Δ tumors) the region containing the MYC oncogene at 128.8 Mb.

Under the designed parameters (signal: sine wave, signal amplitude Vpp: 5 V and Vpp: 4 V, frequency: 300 kHz) of Tumor treating fields (TTFields) with the sprayed liquid metal electrode, four mice tumor groups became diminishing after 1 week of treatment.

A cohort of 80 animals received 1×106 SKOV-3-Luc cells (40 mice, tumor group) or saline (40 mice, control group) on day 0. On days 9, 15, 21 and 28 p.i., all live animals inoculated with cancer cells were optically imaged to obtain the bioluminescent signals from engrafted SKOV-3-Luc (Caliper Life Sciences, Hopkinton, MA).

We used the KC-SMART method [ 18] to identify significantly recurrent genomic aberrations in the aCGH data of the mouse mammary tumor groups.

For clarity, we refer to the classification of mouse tumors as "groups" to distinguish them from human classes that are termed "subtypes".

Our data indicate that amplification of the MYC locus and loss of the RB/INTS6 locus occurs in all mouse and human tumor groups, and that AURKA amplification occurs in mouse and human BRCA2-mutated tumors.