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However, small chemical compounds are much safer and have shown more advantageous in modulating cell function and cell fate changes (Xu et al., 2008).
Extracellular matrix, in addition to cardiac cells, is essential to maintain the integrity of cardiac tissue and plays an important role not only in providing structural and mechanical support but also in modulating cell function.
Several studies have emphasized the influence of environmental cues, antigen dose, and specificity of the APCs recruited to the T cell activation site in shaping the response by modulating cell function (reviewed in [27]).
Several studies have emphasized the influence of antigen dose, microenvironment, and specificity of the APCs recruited to the CD8+ T-cell activation site in shaping the response by modulating cell function [43].
These pathways play a key role in modulating cell function in response to extracellular and intracellular stimuli.
Besides their potential as biomarkers, circulating miRNAs may act as a delivery system and could play a previously unrecognized role in modulating cell function.
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Moreover, in response to metabolic and genetic stress mitochondria and nucleus engage in bidirectional signaling pathways, which modulate cell function [4, 34, 35].
This strategy may represent the next paradigm in our ability to modulate cell function and offers a unique avenue for the treatment of disease.
The study of how physical and biochemical signals collectively modulate cell function not only brings forth a more holistic understanding of cell (patho biology, but it also creates opportunities to control material properties to improve culture platforms for research and drug screening and aid in the rationale design of biomaterials for molecular therapy and tissue engineering applications.
Thus, taken together these data suggest that L1 is able to regulate sialylation and fucosylation to modulate cell function via a PLCγ dependent pathway.
A number of important questions remain to be addressed in our understanding of how RLS modulate cell function.
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affecting cell function
controlling cell function
modulating protein function
modulating cell signaling
modulating synapse function
modulating cell specificity
modulating cell autophagy
modulating cell proliferation
modulating cell growth
modulating cell fate
modulating cell viability
modulating cell survival
modulating cell death
modulating cell motility
modulating cell morphology
modulating brain function
modulating cell mobility
modulating cell adhesion
modulating cell migration
modulating differentiation function
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