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Given its role in modulating cell proliferation, it is not surprising that p16 alterations are one of the most common genetic/epigenetic alterations in cancer.
It has been studied as a PDZ antagonist in modulating cell proliferation, polarity, migration and stress response [17], [ 22], [ 26], [ 27].
The exact role of PAF in modulating cell proliferation, differentiation or transformation is unclear.
This is suggestive that COL1A2 may contribute to the formation of various cancers by modulating cell proliferation and migration.
These voltage activated K+ channels in the SCLC cell lines have a role in modulating cell proliferation [ 21].
The loci regulating RMS cell proliferation did not overlap with the suggestive loci modulating cell proliferation in the SGZ.
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The expression of p53 and p21 proteins is crucial to cell cycle control, and tumor suppressor genes including these can modulate cell proliferation by modulating cell cycle progression [ 13].
Contradictory findings from various cell culture systems support the view that EpCAM expression can modulate cell proliferation, differentiation and migration, but the outcome of modulation is strongly dependent on cell type and origin [ 16- 18].
Because CDK6 is essential for the regulation of cell proliferation, we evaluated whether miR-29b would modulate cell proliferation via binding to CDK6 in osteosarcoma cells.
Several gene targets of Hippo signaling have been identified in Drosophila, including cyclin E, diap1, and the microRNA bantam, which may modulate cell proliferation and survival [1],[12],[14],[28],[29].
Our interest is in lysophosphatidylinositol and the glycerophosphoinositols, which modulate cell proliferation and G-protein-dependent activities such as adenylyl cyclase and phospholipase A2.
More suggestions(16)
modulating cell specificity
modulating cell autophagy
modulating cell growth
modulating growth proliferation
modulating cell fate
modulating progenitor proliferation
modulating cell viability
modulating hepatocyte proliferation
modulating cell survival
modulating cell death
modulating cell motility
modulating cell morphology
modulating differentiation proliferation
modulating cell mobility
modulating cell adhesion
modulating cell migration
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