Sentence examples for modulating protein function from inspiring English sources

Outside of ER, PDI has been reported to serve as switches for modulating protein function in some cases (Hogg 2003; Wouters et al. 2010).

Reliable determination of protein-protein interaction sites is of critical importance for structure-based design of small molecules modulating protein function through macromolecular interfaces.

Allosteric ligand-binding sites offer great potential for modulating protein function, but are often difficult to visualize.

Protein kinases and phosphatases regulate protein phosphorylation, a critical means of modulating protein function, stability and localization.

The gene TiPARP is a target of TCDD that may contribute to multiple responses to TCDD by modulating protein function through poly ADP-ribosylation [ 26].

Meanwhile, it is not known how AS events are conserved and involved in modulating protein function in wood formation of tree species.

Since β-turns usually occur on the exposed surface of a protein, they are well suited to participate in ligand binding, molecular recognition, protein-protein, or protein-nucleic acid interactions, thus modulating protein functions and intermolecular interactions.

Splicing can modulate protein function by changing functional domains, affinities for assembly of heteromeric complexes, or altering mRNA stability.

Upon molecular recognition a ligand can modulate protein function, thereby enhancing, inhibiting or modulating its activity.

It modulates protein function by binding to and detaching from intracellular zinc-dependent proteins.

Thus, there is an urgent need for efficient platforms to develop probes that can modulate protein function in cells to validate drug targets and to develop therapeutic leads.