Sentence examples for modulating cell motility from inspiring English sources

Four and a half LIM domain protein-2 (FHL2) is part of the focal adhesion structures modulating cell motility.

Dysregulation of Src has been linked to oncogenesis process for many years [52], and it is also known to play a role in metastasis by modulating cell motility and invasive abilities in skin, breast and colon cancers [53].

HtrA1 can interfere with secreted Tgf β and BMPs proteins, and operates as microtubule-associated protein, modulating cell motility and cell polarity.

Loss- and gain-of-function studies demonstrate the ability of T-cadherin to modulate cell motility and growth.

Manipulations that change the stiffness of these 3D scaffolds often alter other matrix parameters that can modulate cell motility independently or synergistically, making observations less predictive of how cells behave when migrating in 3D.

Recently, it has been demonstrated that the tumor suppression function of p27 resides not only in the ability to inhibit Cyclins/CDKs complexes through its N-terminal domain but also in the capacity to modulate cell motility through its C-terminal portion.

The mechanisms whereby S100A4 modulates cell motility are unknown.

The actin binding protein CapG modulates cell motility by interacting with the cytoskeleton.

Furthermore, it can modulate cell motility and invasion in breast cancer cell lines (Bai et al, 2000; Li et al, 2008a, 2008b).

Deregulation of actin cytoskeletons caused by weakened cell adhesion directly modulates cell motility, proliferation, and death, providing a molecular basis for the histologic changes in prostate tumorigenesis.

While p27 restrains normal cell proliferation through cyclin-Cdk2 inhibition [ 9], it can also modulate cell motility through mechanisms involving its C-terminal domain [ 31, 32].