Sentence examples for modulating activation of from inspiring English sources

On the other hand, the recessive resistance gene xa5 is an allele of the general transcription factors TFIIAγ (Iyer and McCouch 2004), which probably confer resistance by modulating activation of other TALE targets.

Collectively, our data indicates that constitutive hepatocyte COX-2 expression ameliorates NASH and liver fibrosis development in mice by reducing inflammation, oxidative stress and apoptosis and by modulating activation of hepatic stellate cells, respectively, suggesting a possible protective role for COX-2 induction in NASH/NAFLD progression.

Mechanistic data suggest that DDT could play a role in pancreatic cancer by modulating activation of the oncogene K-ras (Porta et al. 1999).

A role for ROS is well established as an upstream mediator of autophagy by modulating activation of AMPK, MTOR, and MAPKs.

Recent evidence has highlighted an important role for specific integrin receptors in modulating activation of TGF-β via binding to an RGD integrin binding motif present in the latency-associated peptide (LAP) region of latent TGF-β.

Moreover, it is possible that APS exerts its beneficial effects in acne patients via modulating activation of the mechanistic/mammalian target of rapamycin complex 1 (mTORC1) which is a master regulator of cellular metabolism.

Paroxetine dose-dependently modulates activation of the entire motor pathway in a way that favors motor output.

Recent evidence suggest that 1,25(OH)2D3 may affect T-dependent responses in cattle; however, mechanisms by which this vitamin modulates activation of bovine T cells are unclear.

Together, these data suggest that STAT3 directly modulates activation of the PAX3 promoter.

We hypothesised that the differential VEGF-A isoform-specific regulation of cytosolic calcium ion flux could modulate activation of endothelial NFATc2.

In the African American group, rs16965628 significantly modulated activation of the ventrolateral PFC in the PTSD group, but not the non-PTSD group [F 5,22) = 10.9, p <.0001].