Suggestions(2)
Exact(3)
Previous authors have hypothesized that additional factors such as c-MYC and KLF4 facilitate reprogramming by modulating accessibility of the OCT4 and SOX2 loci [24], [25].
We cannot rule out that TRM4A contains other regulatory functions, for example regulating mC stability or modulating accessibility of mC sites to RNA binding proteins.
The epigenetic information stored in chromatin structure, which can be altered by DNA methylation, histone modifications and nucleosome positioning, affects the transcriptional competence by providing protein binding sites and modulating accessibility of transcription machinery [ 2– 8].
Similar(57)
Nucleosome depletion or exchange at the promoter can modulate accessibility of DNA to transcription factors.
Here, we used a post-expression cysteine (Cys -to-dehydrolanine (Dha) Cys -to-dehydrolaninetegy to identify a water-mediated motif that modulates aCys -to-dehydrolaninerotein tyrosine phosphatase A (PtpA) catalytic pocket.
However, these amino acids might not only change the binding of GTP, but also modulate accessibility of the binding site for GTP or binding of some regulatory protein.
RNA structure can play a role in regulating translation through modulating the accessibility of codons.
Hence, SPR2 dynamics provides an efficient means of cytoskeletal regulation by directly modulating the accessibility of MT crossovers to katanin.
Post-translational modifications of histones represent an important mechanism modulating the accessibility of chromatin and contributing to the recruitment of other proteins to chromatin [ 2].
It also plays a crucial role in regulation of DNA-related processes by modulating the accessibility of DNA to regulatory proteins.
This particular method of grafting results in a complex polymer microstructure allowing for further development in the ability to modulate the accessibility of guests to a MOF.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com