Sentence examples for affecting activation of from inspiring English sources

cIAP1/2 attaches K63-polyubiquitin linkages to TRAF3, TRAF6 97 and possibly other components, thereby positively affecting activation of IRF3 and NF-κB.

lncRNA-Smad7 appears to function as a downstream anti-apoptotic factor of TGF-β in the mouse breast cancer cell line JygMC(A) without affecting activation of Smad2 and induction of EMT.

As proposed, we tested whether the inhibitors of glycosylation affected activation of adenylyl cyclase activity by VIP and forskolin.

These early pre-clinical findings suggest that hapten structure affects activation of B cells, and that variations in the frequency of early-activated hapten-specific B cell subsets underlie individual differences in vaccine efficacy.

In contrast to AhR, Arnt did not seem to affect activation of the classical NF-κB pathway as assessed by p65-luciferace activity or p65 phosphorylation.

It also did not affect activation of the PVN or SON.

Thus, inhibition of Tpl2 will not affect activation of ERK1/2 by other agonists, like growth factors, which has been proven protective in several diseases, such as myocardial and cerebral ischemia-reperfusion injury [40, 41].

Mutation to aspartate or alanine affected activation of a reporter by full-length Adr1, and in vivo promoter binding.

Therefore, we next addressed whether TRAF6-deficiency affects activation of IRF 3 and IRF7 in MEF cells.

Besides epigenetic factors, also availability and abundance of single nucleotides affect activation of origins of replication [34] and could play a role in variations of replication fork rates.

This suggested that several residues in this area indeed affected activation of expression by 2-HBP, but only Glu184 seemed absolutely critical.