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Since IL-4 has been shown to modulate growth of various tumour cell lines (Puri, 1995), we examined whether it modulated growth of human medulloblastoma cell lines.
In the present case, OLA serves as a capping surfactant that can modulate growth of CuO nanocrystals via hydrophobic forces between the OLA molecules.
These results indicate that IL-4 does not modulate growth of medulloblastoma cell lines.
Summary: The Drosophila miRNA bantam regulates the expression of Brat and Prospero – known inhibitors of brain neuroblast proliferation – to modulate growth of the central brain.
Barrenäs et al. (2000) describe evidence that growth-related phenotypes in Turner syndrome (and other aneuploidies) are mediated by effects of aneuploidy on rates of cell turnover, which in Turner syndrome differentially modulate growth of SHOX-regulated mesodermal tissues with the shortest cell cycle time and highest cell cycle rate.
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The discovery that blockade of hormone receptors on certain cancer cells could modulate growth patterns of these cells both in vitro and in vivo provided a massive step forward in so-called hormone sensitive cancers.
GST-mda7 failed to significantly modulate growth characteristics of 4 different melanoma cell lines (Fig. 7).
Thereafter it has been demonstrated that IL-24 is in fact a typical cytokine as it binds to specific receptors, it is secreted, it activates the JAK/STAT signaling pathway and it can modulate growth characteristics of responsive cells [7] [10].
Because several authors found that topography and small-scale variability in edaphic conditions modulate growth response of trees to climate (Orwig and Abrams 1997; Oberhuber and Kofler 2000; Fekedulegen et al. 2003), a mixed-species stand was analysed to determine how environmental conditions affect growth.
Modulation of these MAP kinase pathways has also been demonstrated in various prostate cancer cell lines by growth factors, cytokines and variety of agents that modulate growth and apoptosis of these cells.
Looking at the induced genes that were specifically expressed in response to the drug treatment, it is clear that efavirenz triggers the expression of distinct set of genes that can functionally modulate growth and differentiation of cancer cells.
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