Sentence examples for modulate translation of from inspiring English sources
However, HuR has also been shown to modulate translation of a number of targets [35], [36], [37].
Thus, expression of miR-130a and FOG-2 overlaps in the heart and lung and suggests that in these tissues miR-130a might modulate translation of the FOG-2 message.
As uORFs commonly modulate translation of downstream ORFs (dORFs) (25), we investigated whether the c.−95T > G mutation affected EPHRIN-B1 production.
The transcript encoding GCN4, a bZIP transcription factor with homology to mammalian ATF4, has four uORFs that modulate translation of its coding sequence upon stress.
Since hnRNP family proteins are known to accompany RNA from the gene through nuclear pores and into polysomes (Visa et al. 1996) the hnRNP family proteins detected in ER maybe associated with membrane-bound polysomes and modulate translation of specific proteins relevant to protein synthesis.
Our findings further establish that although the end result of mTOR inhibition is a global decrease in protein synthesis, differential inhibition of mTOR signal transduction may distinctly modulate translation of specific subsets of mRNAs that control the key cellular processes responsible for cell fate.
For example it was possible that Hfq directly modulates translation of smpB and therefore all of the effects observed for smpB could be related to Hfq.
Translatome analysis of mTOR downstream target genes established that differential inhibition of mTOR by EtOH and INK128 distinctly modulates translation of specific subsets of mRNAs involved in cell growth and survival, leading to differential cellular response and survival.
The association of FUS with RNA granules that modulate translation under conditions of induced stress has emerged as an active area of research, as discussed later.
Furthermore, it needs to be established if this ability of AKT to modulate translation elongation can contribute to AKT-driven tumourigenesis.
Fifth, antisense RNAs may modulate translation [50].
