Sentence examples for modulate transcription of from inspiring English sources

Phosphorylation of Thr4, however, appears to selectively modulate transcription of specific classes of genes.

For example, spatial proximity is necessary for enhancers to modulate transcription of target genes (for example, refs 5, 6, 7), and clustering of chromatin near the nuclear lamina is correlated with gene silencing and replication timing8,9.

Using cultured myocytes and transgenic mouse models, we have defined features of signaling cascades that modulate transcription of specific contractile protein isoforms, mitochondrial biogenesis, and myocyte mass.

This suggests that the peptide may modulate transcription of the cyclins while affecting the stability of HPV16E7 and pRb protein.

These observations suggest that REST and CoREST modulate transcription of this repertoire of epigenetic factors in a glial subtype and developmental stage specific manner.

These data suggested that one or more regulatory elements might modulate transcription of frataxin under varying metabolic conditions such as iron starvation.

Activated JNK phosphorylates c-Jun, a nuclear transcription factor, to increase AP-1 transcriptional activity, which modulates transcription of a number of apoptosis genes such as FasL.

When synthesized in the nucleus by SphK2, S1P is reported to inhibit histone deacetylase 1 and 2 (HDAC 1/2) with the effect of modulating transcription of, for example, cyclin dependent inhibitor p21 and the transcriptional regulator c-fos.

Here, we show that turnover of nuclear NPR1 protein plays an important role in modulating transcription of its target genes.

HIF-1 is a key regulator of hypoxic responses and modulates transcription of numerous genes associated with adaptation to hypoxia [12].

Nuclear factor I (NFI) belongs to a family of transcription factors that play important roles in modulating transcription of differentiation-associated genes [44].