Sentence examples for mediate oligomerization of from inspiring English sources

The transmembrane domains mediate oligomerization of LMP1 molecules in the plasma membrane, a prerequisite for LMP1 function [1], [9].

The N-terminus of NCOA4 consists of predicted coiled coil domains that have been previously shown to mediate oligomerization of NCOA4 Monacoo et al., 2001).

Cytokines mediate oligomerization of the γc chain with the appropriate cytokine receptor chain, which leads to Janus kinase 1 (Jand) and Janus kinase 3 (Jactivationandon and phosphorylation of critical tyrosine residues in the receptor chains (Fig.  4) [ 23, 36].

In order to analyze Hsp27-eIF4E interaction, we used Hsp27 deletion mutants previously described by Al-Madhoun et al. The C-terminal mutant Hsp27 N1 (1-93) lacks part of the α-crystallin domain, believed to mediate oligomerization of Hsp27.

Monomeric IKK2 is observed to undergo trans autophosphorylation at elevated concentrations only, and this forced interaction is dependent upon the surfaces that mediate oligomerization of open IKK2 dimers in the X-ray crystal structure.

It is believed that BCL10 mediates oligomerization of MALT1, which allows the formation of a complex with TRAF6.

A signature of TSP subgroups A and B is associated with the heptad-repeat coiled-coil domain that mediates oligomerization of TSP subunits.

The permanent association of the fusion protein with the lipid rafts [24], [25] or its oligomerization [23] via the first BIR domain bypasses the normal requirement of BCL10-mediated oligomerization of the MALT1-TRAF6 complex, resulting in TRAF6-mediated NF-κB activation without the need for antigen receptor triggering [26].

This indicates that SUMOylation-mediated oligomerization of VHL is dependent on its oligomerization domain.

To estimate the likelihood of whether the crystallographic interfaces mediate oligomerization in solution, we performed a bioinformatic analysis with PISA (Protein Surfaces, Interfaces and Assemblies).

Moreover, the specific regions of the various coatomer subunits that mediate oligomerization during COPI cage formation are not precisely known [ 6, 35, 36].