Sentence examples for binding and alteration of from inspiring English sources

Another possibility explaining the function of p30 involves the binding and alteration of known cellular proteins involved in RNA modification and transport.

Fluorescence binding assays indicate a significant loss of binding and alteration of enzyme regulation for individual mutants of these surface residues (E16, F17, and E20).

This region is necessary for protein binding and alteration of the buried Glycine residue with larger Serine residue might abolish the core structure of the domain and affect protein binding.

A single transient stretch may acutely fluidize airway smooth muscle which is normally solid, leading to perturbed equilibrium of myosin binding and alteration of airway smooth muscle mechanical properties (the cell becomes much less stiff and much more viscous) [ 30].

The top 96 differentially-expressed genes (P < 0.05, fold change > 2.5) between S. Typhi-infected children and other bacteremia(Additional file 1) included genes that are involved in ligand binding and alteration of cell composition such as lipocalin (LCN2) and prosaposin (PSAP).

It has been reported that the periplasmic space comprises 40% of the total volume of the cells and it includes solutes and proteins that are involved in a wide variety of functions, ranging between nutrient binding, transport, electron transport, and alteration of substances toxic to the cell [ 17].

EWS-FLI1 driven oncogenesis is thought to rely mainly on DNA binding and subsequent alteration of the expression of specific target genes.

A variety of molecular mechanisms for resistance to broad-spectrum β-lactams have been reported in A. baumannii, such as mutations of penicillin-binding proteins and alterations of membrane permeability, but the most common mechanism is attributed to the presence of β-lactamases encoded by either chromosomes or plasmids (2, 10, 11 ).

Biofilm formation [12] and alteration of binding sites of drug [13] are the mechanisms of acquiring resistance to vancomycin.

IT has also been used in genetic engineering in the design and alteration of binding sites, and has been used in the design of constructs for transgenic animal models.

It has been proposed that lead acts to increase production of IgE through direct or indirect stimulation of B-cells or through the binding and subsequent alteration of allergens that stimulate the allergenic immune response (Annesi-Maesano et al. 2003; Lutz et al. 1999).