Sentence examples for binding and neutralisation of from inspiring English sources

BCL-GS was reported to kill cells by binding and neutralisation of prosurvival BCL-XL.

AZD9773 binding and neutralisation of primate TNFα were assessed using surface plasmon resonance and TNFα-mediated cytotoxicity assay using L929 cells, respectively.

This effect is due to binding and neutralisation of the receptor activator of the nuclear factor- κB ligand, thereby neutralizing its functions and negatively regulating osteoclast differentiation, activity, and survival resorption [ 5, 8].

Characterisation of the binding and neutralisation properties of all the purified 2G12 variants from plants showed that these were generally similar to those of the Chinese hamster ovary (CHO) cell-produced 2G12.

Since variability of the BoNT gene and protein sequence within botulinum neurotoxin subtypes A has been reported and these sequence variations impact on antibody binding and neutralisation [21], the capacity of mouse and chimeric antibodies to neutralise BoNT/A2 and /A3 was evaluated using a mouse neutralisation assay with 5 estimated MLD50 per mouse of each toxin subtype.

Either way, to conceive of the government of Hong Kong as being an exercise in the identification and neutralisation of dissidents or all those deemed to be "unpatriotic" would be profoundly counterproductive.

However in this model system, IL-8 alone had no pro-proliferative action and neutralisation of IL-8 did not affect the stimulatory action of IL-1β.

Indeed, reduction in binding affinity and neutralisation between BoNT/A1 and BoNT/A2 has already been noted [21].

Such binding results in either neutralisation of the antigen itself or, when the antigen is bound to a cell (e.g., bacteria), destruction of that cell via activation of the complement system, neutrophil degranulation, or phagocytosis by macrophages.

Two potent cytotoxins, TcdA and TcdB are the prime mediators of the syndrome and rapid neutralisation of these would afford significant benefits in disease management.

This clearly indicates that one changed arginine sensor is sufficient to lead to channel closure and that neutralisation of both sensors is necessary for channel opening.