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We initially showed that robotic motion planning permitted one to determine the energy of binding and dissociation of ligands from protein binding sites (Singh et al., 1999).
The binding and dissociation of estrogen receptors ERα and ERβ to different ligands is analyzed within the fractal framework.
Thus, the analysis of the binding and dissociation of beta amyloid (Aμ) in solution to fibril surfaces is discussed.
This method will be illustrated by utilizing data that have been obtained when using this approach to measure the binding and dissociation of various drugs with the serum transport proteins human serum albumin and alpha1-acid glycoprotein.
We examine the influence of the rate of binding and dissociation of GnRH on the GnRH movement down the chamber.
We then tested if Rpn4* could affect the binding and dissociation of the proteasome to and from a DBS.
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Moreover, it was also found that the DS of the hydrophobic moiety can adjust the balance between DNA binding ability and dissociation of polyplexes, significantly affecting the transfection efficiency.
In the washout setting, strikingly, the inhibition of HDAC activity by vorinostat was immediately lost after the washout, suggesting very fast binding kinetics and dissociation of the inhibitor from its target.
The difference in chemical properties of these polycations are of interest as they have different p Ka values and hydrophobicity profiles, which can affect cell membrane interaction, the polymer nucleic acid binding strength, and dissociation of these species once within the cell.
Also, Marchesini et al. [ 93] successfully measured the binding and dissociation kinetics of a test set of seven low molecular weight paralytic shellfish poisons binding to immobilized saxitoxin monoclonal antibody.
Therefore, in addition to imaging of live eukaryotic cells and isolated intracellular organelles, this combined system allows simultaneously observing, for example, the dynamic binding and dissociation events of fluorescent ligands on single protein molecules and the structural changes of the molecules concomitantly occurring with the ligand binding and dissociation.
More suggestions(15)
binding and releasing of
binding and mechanism of
binding and stabilization of
binding and internalization of
binding and activation of
binding and transport of
binding and selectivity of
binding and accumulation of
binding and invoking of
binding and discovery of
binding and hemolysis of
binding and hybridization of
binding and enactment of
binding and uptake of
binding and migration of
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