Sentence examples for mutations may drive from inspiring English sources

As TGFBR2 and ACVR2 mutations may drive the pathogenesis of colorectal cancers, our human data is consistent with the virulence of tumor formation in Lynch syndrome.

These mutations may drive tumour development as they promote cell proliferation in Wilms tumour cells.

Alternatively, TP53 or PIK3CA mutations may drive cancers originating from different cell types.

However, as the STAT3 and STAT5 mutation-negative patients also have monoclonal expansion of LGL cells, other somatic mutations may drive these expansions.

In addition, the sequencing of breast cancer patient genomes suggests that infrequent mutations may drive tumor progression through known signaling pathways, such as the Raf MEK1/2 ERK1/2 cascade [ 5].

Mutation may drive the system far from equilibrium and be another source of non-zero probability flux.

Mutation may drive variation in nucleotide content, if different bacterial lineages vary in their mutational biases.

However, caution should be exercised because of the possible presence of downstream oncogenic mutations that may drive treatment resistance.

Their findings support the idea that CTRC variants do not increase susceptibility to trypsin activation as seen in patients with cationic trypsinogen mutations, but may drive stellate cells to produce fibrosis.

Taken together, these results can be interpreted to suggest that existence of trisomy 7 and the other introduced genetic alterations lead to the acquisition of additional mutations that may drive CRC initiation and progression.1CT7 and partially transformed A1309 cells may harbor the genetic background mimicking early stages CRC.

We present unprecedented data whereby these combined micronutrients effectively promotes tumor dormancy in early prostate cancer, following initiation mutations that may drive the angiogenesis-dependent response of the tumor, by inducing platelet factor-4 expression and concentrating it at the tumor endothelium through enhanced platelet binding.