Sentence examples for mutations may represent from inspiring English sources

The development of epithelial cancers requires multiple mutations (Fisher, 1958), and the stepwise accumulation of these mutations may represent an inherent mutator phenotype (Loeb, 1991).

Using base editors to directly repair point mutations may represent an efficient and highly specific alternative.

Thus, enhanced microtubule polymerization and reduced dynamic instability caused by tubulin mutations may represent a survival mechanism against microtubule de-stabilizing compounds.

Men with germ line genetic mutations may represent such a high risk group.

These results suggest that the phenotypes associated with genes containing these mutations may represent specific characteristics of these breeds.

Non-ETS-specific mutations may represent a convergent pathway to later stage disease and subsequent castrate resistance.

This mutation may represent a candidate frequent mutation in the Italian population.

Within a family, carrying a risk mutation may represent risk for a constellation of developmental phenotypes.

Indeed, this mutation may represent the initial stages of evolutionary divergence between these 2 genes.

Finally, bladder cancers harboring a beta-catenin mutation may represent aggressive biological behavior with enhanced proliferating activity [ 44].

We thus hypothesised that KRAS genome amplification, rather than mutation, may represent a predominant mechanism for KRAS activation in gastric cancer.