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Our results suggest that synonymous mutations may play an underappreciated role in adaptive evolution.
Small molecule compounds that target specific receptors or mutations may play a significant role as their side-effect profiles are tolerable.
Interestingly, PIK3CA hotspot point mutations were identified in associated ductal carcinoma in situ (3/14) and hyperplasia (atypical ductal hyperplasia [2/3], usual ductal hyperplasia [2/3], columnar cell change [1/5]), suggesting that PIK3CA mutations may play a role in breast epithelial proliferation.
The results included in this report also show that somatic de novo mutations may play a significant role in the development of schizophrenia.
HA mutations may play a role in reduced susceptibility to NAIs in drug patients, although direct experimental evidence is lacking at this time.
Several gene mutations may play a role at this stage.
Similar(27)
Our method suggests that two LoF mutations previously implicated in IBD may contribute to ASD, and one ASD-implicated LoF mutation may play a role in IBD.
She believes a similar gene and mutation may play a role in ataxias, human coordination disorders.
Given that the majority of the viruses gained the V100I mutation during a short period of time when the pandemic alert level was raised from phase 4 to phase 6 (Table 3), this mutation may play a role in the increased transmissibility or infection of the 2009 H1N1pdm.
SPINK1 IVS3+2T>C mutation may play an important role in the pathogenesis of Chinese paediatric ICP.
These observations suggested that the R337H mutation may play a role in breast tumorigenesis.
More suggestions(15)
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mutations may respond
mutations may transform
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