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Exact(7)
Additional testing of expanded KRAS/NRAS mutations is recommended.
Additional testing of extended KRAS/NRAS mutations is recommended.
Thus screening for BCR-ABL1 mutations is recommended particularly in patients experiencing poor response to treatment.
Genetic screening for SDHB, C and D germline mutations is recommended for patients with paraganglioma/pheochromocytoma and SDH deficient GISTs.
In PND patients, screening of the KCNJ11 mutations is recommended, and if it is negative, mutations in other genes should be investigated (e.g., insulin gene, ABCC8, etc).
Detection of KIT or PDGFRA mutations is recommended in advanced GISTs because they are highly predictive of tumor response to RTK inhibitors, as well as in KIT-negative cases to confirm diagnosis.
Similar(53)
As a result, routine screening of CDH1 mutation is recommended in diffuse type familial GC.
In some laboratories, it may be desirable to screen for specific prevalent mutations first, but in the absence of biallelic mutations it is recommended that all possible mutations should be screened, for adequate diagnostic testing.
Thus, mutation testing is recommended when imatinib is being considered for treatment.
BCR-ABL1 mutation analysis is recommended for chronic myeloid leukaemia patients.
Although still under debate, CRC screening in monoallelic mutation carriers is recommended for first-degree relatives of a patient with sporadic CRC.
Related(20)
mutations is incorporated
mutations is proposed
mutations is considered
mutations is introduced
mutations is rejected
mutations is rendered
deployment is recommended
transfer is recommended
move is recommended
mutations is performed
mutations is taken
mutations is known
mutations is shown
mutations is expected
mutations is given
mutations is maintained
mutations is estimated
mutations is assumed
mutations is limited
mutations is correlated
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