Sentence examples for mutations is limited from inspiring English sources

This coupling of DNA damage to phenotypic persistence may increase genetic diversity specifically in severe stress conditions, where diversity is beneficial but the ability to generate de novo mutations is limited.

While the characterization of the effects of most αB-crystallin mutations is limited, the effects of the R120G mutation on protein structure and chaperone activity have been extensively investigated [27] [30].

Thus, histopathological estimates of tumor-cell content are not predictive of the frequency of mutant alleles, while the ability to detect mutations is limited by the allele frequency but not by the tumor cell content.

The predictive power of the Koel mutations is limited and improvement restricted to a few years.

BRCA/FA pathway genes are well known tumor suppressors, 21– 23 but the percentage of mutations is limited.

Consequently, opportunity for accumulating DNA mutations is limited, resulting in relatively little genetic variation within the species.

The second prediction arising from this hypothesis is that under stressful conditions, where directional and purifying selection are important, sexual populations will display greater rates of adaptation compared with asexuals, and that an elevated mutation rate will effect the difference in rate of adaptation between sexuals and asexuals only if the supply of beneficial mutations is limiting.

For instance, the researchers have found the altered proteins only in brain cells that control motor functions; they cannot explain why the mutations are limited to these cells.

Studies assessing the impact of other molecular alterations rather than KRAS mutations are limited.

All proteolytically inactive mutations were limited to the globular Domain 1, providing evidence that this part of the passenger domain solely encodes the proteolytic activity.

Although, it should be noted that samples with mutations are limited.