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A new method for the identification of point mutations is proposed.
In this article, an innovative GA with a special chromosome encoding, two modified crossovers and two modified mutations is proposed to solve the problem.
The combined use of molecular dynamics free energy simulations to study one binding process thoroughly, followed by molecular dynamics and Poisson-Boltzmann free energy calculations to study a series of related ligands or mutations is proposed as a paradigm for protein or ligand design.
This difference in phenotypic expression of proteotoxic mutations is proposed to be due, at least in part, to the variability in genetic background.
The activation of MEK and then ERK in response to oncogenic NRAS and BRAF mutations is proposed to be the basis of a MAPK pathway addiction by these cells [ 37].
Similar(55)
Molecular modeling simulations were applied on the homology model of PLE-1, the major isoenzyme in the crude PLE, and distinct sites of mutations were proposed and produced in the laboratory.
TP53 mutations were proposed as the driver mutations in colorectal carcinogenesis [ 1].
Other oncogenic mutations are proposed to primarily mediate an interaction with the PM [ 25, 26].
Since SPINK1 mutations are proposed a modifier role, we also investigated its interaction with the ACE gene variant.
Their mutations were proposed to verify the importance of the particular step or the function of chemicals.
These somatic missense mutations were proposed to increase the kinase activity of PIK3CA contributing to cellular transformation.
Related(20)
transfers is proposed
mutations is referred
moves is proposed
mutations is identified
transfer is proposed
deployment is proposed
mutations is known
mutations is shown
mutations is needed
mutations is reported
mutations is indicated
mutations is summarized
mutations is taken
mutations is assumed
mutations is found
mutations is correlated
mutations is thought
mutations is recommended
mutations is limited
mutations is likely
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