Sentence examples for mutation that disables from inspiring English sources

It turns out, the researchers report in the Friday issue of the journal Science, that those individuals who barely responded have a mutation that disables one of their two copies of a gene called apoC-III.

The AIDS virus enters the T cells of the immune system by latching on to a receptor called CCR5, but about 10percentt of Europeans have a mutation that disables the CCR5 gene.

In mice with a mutation that disables the inner clock, the gut bacteria didn't exhibit the same fluctuations, in either population or activity, in response to light and dark suggesting that the animal's clock somehow controls that of the bacteria.

To further simulate a paternal genome, the team used immature oocytes that carried a mutation that disables a gene implicated in a cascade of imprinting events thought to derail parthenote development.

Using gene sets defining mature myeloid, erythroid and megakaryocytic cells, we previously observed depletion of mature GM genes in HSCs homozygous for a Cebpa point mutation that disables C/EBPα DNA binding (K313KK or KK allele) (Bereshchenko et al, 2009).

Some people with Crohn's disease have genetic mutations that disable the salubrious effects of IL-10.

I demonstrate that 60mer oligos with 29 bp of homology drive efficient knock-in of point mutations, and that disabling nonhomologous end joining by RNAi inactivation of the cku-80 gene significantly improves knock-in efficiency.

Ms. Terry said her next goal was for scientists to analyze the different mutations that could disable the ABCC6 gene to learn the reasons for the various manifestations in different people.

Dominantly inherited nonsense and missense mutations that completely disable MC4R represent the most common apparent molecular mechanism for obesity; however, recessive modes of inheritance are also encountered (15).

Alternatively, Pijls et al [ 29] hypothesized that once a population had reached fixation for the PI- Wolbachia infection and sexual reproduction has ceased, those mutations that would disable costly female traits involved with sexual reproduction would be selected.

This new method uses the Cre- loxP system to induce mutations in a tissue- and temporal-specific manner [ 7], and mimics human disease by producing mice in which one of the two Brca1 genes has been disabled while the other carries a mutation that enables it to be disabled in mammary tissue later in the life of the mouse.