Sentence examples for mutation that impedes from inspiring English sources

The trans-binding signal could be isolated by mixing an AB module carrying a mutation that precludes binding to helix A (A343D) with an AB module with a mutation that impedes binding to helix B (S511D 41.

Thus, the CUL3Δ403 459 mutation is a novel physiological example of the importance of this CRL rigidity and to our knowledge the first example of a human mutation that impedes the scaffolding function of a Cullin.

In turn, mutations that impeded these self-restricting mechanisms caused increased pathogen motility, via enhanced growth rate, resulting in hypervirulence.

The failure of some patients to respond to AMN107, especially those with more advanced disease, might arise due to development of new mutations that impede the interaction between AMN107 and BCR-ABL.

However, another mutation that impeded hTR binding did not alter this subcellular localization.

In the present report we have addressed this question by investigating whether a mutation that decreases sensitivity of FMDV to R can impede extinction of the virus in the course of cytolytic passages of the virus.

We discovered 30 mutants containing mutations that impeded growth enough to prevent visible colony formation on minimal medium.

Stable docking of the E helix is a pivotal step in the apomyoglobin folding pathway, and mutations that impede this process slow the overall folding rate.

But that impedes deep understanding.

A systems-pharmacology approach reveals that the combined off-target activity of two kinase inhibitors that impedes MAPK signaling to decrease expression of Myc target genes increases apoptosis in CML cells containing gatekeeper mutations in BCR-ABL.

A suppressor mutation that creates.