Sentence examples for mutation that interferes from inspiring English sources

Likewise, The New England Journal of Medicine in June documented a human version of the Belgian Blues, a boy with a genetic mutation that interferes with myostatin.

MPN-BSH activity apparently did not require interaction with endogenous MP because introducing a mutation that interferes with homodimerization (Boer et al., 2014) (MPNm1-BSH) did not impair activity.

This study clearly demonstrates a proof of this principle by combining ΔsecA2 with a second mutation that interferes with virulence of M. tuberculosis, thus generating a novel attenuated candidate mycobacterial vaccine strain with significantly improved safety and efficacy.

The sites of the ADDA mutation that abolishes SubA cleavage and alters the character of the interdomain linker and that of the V461F mutation that interferes with substrate binding are indicated (crosses).

Recently, scientists discovered a mutation that interferes with the movement of the lipid and sugar molecules that make up the outer membrane, which compromises this protective layer and makes the bacteria more susceptible to antibiotics.

The hope for the future is that the next phase of endocrine therapy choices will not be based on small incremental benefits in a broad spectrum of ER-positive tumours, but large benefits in sometimes rather small subgroups of patients defined though the presence of a targetable somatic mutation that interferes with endocrine therapy responsiveness.

In other cases the site where a class II element is cut out of the genome is not repaired correctly, resulting in mutations that interfere with gene regulation and thereby cause cell dysfunction.

Mutations that interfere with the trans interface ablate adhesion, whereas cis interface mutations disrupt stable junction formation.

Alport syndrome, caused by mutations that interfere with the normal assembly of the α3α4α5(IV) collagen network in the glomerular basement membrane (GBM), is the most common inherited glomerular disease leading to renal failure.

Accordingly, mutations that interfere with this pathway result in hypersensitivity to various cell-wall perturbing treatments.

Conversely, SMA mutations that interfere with self-oligomerization of SMN, Y272C and SMNΔ7, had no effect on cleavage.