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Exact(7)
An alternative scenario could be a mutation that inhibits the interaction of the gene with others.
ΔF508 is a processing mutation that inhibits folding in the endoplasmic reticulum and trafficking to the cell surface.
Most surprisingly, the Q153R CPR mutation, a rare disease-causing mutation that inhibits steroidogenic activity, increased the activity of both CYP1A2 and CYP2C19 to 144 and 284%, respectively.
This is achieved by cytoduction, which involves mating donor and recipient yeast in the presence of a kar1 mutation that inhibits efficient nuclear fusion.
These analyses have been conducted with a mouse hepatoma cell line commonly used in AHR signaling work and have been controlled at every step by similar studies done on a derivative cell line bearing a receptor with a missense mutation that inhibits its binding to DNA, hence providing an important biological verification of the results.
Among the ripening mutations, ripening inhibitor (rin) is a well-characterized mutation that inhibits such characteristic phenomena observed during ripening as lycopene accumulation and softening, resulting in non-ripe fruit [ 4].
Similar(46)
She has a gene mutation that caused tuberous sclerosis.
William was born with a genetic mutation that results in achondroplasia, a kind of dwarfism.
That led them to a tiny mutation that made all the difference.
"It has been very hard to find a mutation that abolishes aging," Dr. Rose said.
And he tried to get scientists to find the genetic mutation that causes the disease.
More suggestions(15)
mutation that guarantees
mutation that lets
mutation that disrupts
mutation that abolishes
mutation that closes
mutation that does
mutation that is
mutation that arises
mutation that lowers
mutation that helps
mutation that results
mutation that occurs
mutation that gets
mutation that afflicts
mutation that inactivates
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com