Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
To test the H840A mutation that deactivates the HNH domain, we also injected sgRNA plasmids into P{nos-Cas9 H840A}attp2 embryos.
Similar(59)
When fully induced, the regulatory system is in principle free to lose regulation by neutral drift: mutations that deactivate the repressor do not affect the growth rate.
The truncating mutations are, in fact, clustered as p.W288fs, a four base insertion that deactivates the carboxyl terminus and delocalizes the protein [ 47].
The fourth type of event is termed de-exonization, which is the conversion of an internal exon into an internal portion of an intron by mutations that deactivate splicing signals.
The third type of event is termed de-intronization; in this case, sequences are not deleted from the genome, but rather an intronic sequence is converted into an exonic sequence by mutations that deactivate splicing signals.
It is, it turns out, a potent antioxidant, a chemical that deactivates free radicals.
There is a rare mutation that does the same thing.
Only RASA1, which encodes a Ras-GAP that deactivates H-Ras, was hemizygously deleted in this pathway.
In principle, there are two ways by which cancer cells may escape the damage response during cancer progression and therapy: through genetic mutations that cripple the checkpoint pathway, or by hijacking cellular mechanisms that would naturally deactivate the checkpoint.
Mutations that add or change function?
Somewhere among the genetic disparities must lie the mutation or, more probably, mutations that define us.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com